In the past month you may have noticed that the identifying number associated with the islets you are receiving seems a little longer - not the normal 4 letters followed by three numbers that most researchers came to identify as the UNOS number, representing the donor from whom the pancreas and the isolated islets came. The new label beginning with “RRID:SAMN” followed by 8 numbers is an automated tag called a Research Resource Identifier (RRID). This identifier is generated in collaboration with the National Center for Biotechnology Information (NCBI) and dkNET, through which RRID metadata is catalogued and tracked. IIDP has generated this identifier for every one of their islet preparations, in order to cooperate with the National Institute of Health (NIH) mandates for Rigor and Reproducibility.
In June of 2013, NIH sponsored a workshop to find a solution to the problem of incomplete identification of research resources within papers, and the need for a computational solution for identifying and tracking them in the literature. A working group, the Resource Identification Initiative (RII), was established, comprised of publishers, journal editors, antibody manufacturers and distributors, biocurators, software tool developers, and foundations. RII established a pilot project to test implementation of a system for authors submitting manuscripts to identify research resources through the use of a unique identifier, termed an RRID# in February of 2014. Results of this pilot were published in June of 2015 with revisions submitted the following November 1. After six months of guide notices and blog posts generated by NIH and many journals, on January 25, 2016, NIH mandated that all grant applications follow their published guidelines on Rigor and Reproducibility. A one page guide can be found at https://nexus.od.nih.gov/all/2016/07/31/your-one-page-guide-to-rigor-and-reproducibility/.
As a provider of a valuable resource to hundreds of investigators each year, the IIDP hopes that the provision of an RRID to authenticate human islets from a single donor source, isolated by a specific isolation center, and distributed through our program, will assist in linking experiments published by many investigators, in order to provide a better understanding of the scientific results. 1. The Resource Identification Initiative: A cultural shift in publishing. Bandrowski, A, et al. Brain Behav. 2015 Dec 8;6(1):e00417. doi: 10.1002/brb3.417. eCollection 2016 Jan. PMID: 27110440